Molecular Mechanisms of Cancer
Leadership
Program Leaders: Barbara Kee, PhD, and Scott Oakes, MD
Assistant Program Leader: Alex Muir, PhD
The Molecular Mechanisms of Cancer Program focuses on determining the basic cell signaling and gene expression mechanisms that underlie malignancy. The program brings together basic and translational investigators from 13 departments with a wealth of experience in cancer biology, chemistry, cell signaling, systems biology, developmental biology, and drug discovery.
Key Research Themes
- Uncover how gene expression is controlled through context-specific regulation and epigenetics (DNA and protein modifications that change gene expression without altering DNA sequence)
- Determine the cellular mechanisms underlying altered cell growth, including proliferation, death and metabolism
- Understand the multifaceted mechanisms leading to cancer metastases or spread to distant sites
Nishant Agrawal, MD
Ayman Al-Hendy, MD, PhD
Lev Becker, PhD
Eugene B. Chang, MD
Huanhuan Chen, PhD, PharmD
Jing Chen, PhD
Jason Cheng, MD, PhD
Jill de Jong, MD, PhD
Bryan Dickinson, PhD
Wei Du, PhD
Shannon Elf, PhD
Brandon Faubert, PhD
Lucy Godley, MD, PhD
Geoffrey Greene, PhD
Tong-Chuan He, MD, PhD
Yu Ying He, PhD
Evgeny Izumchenko, PhD
Barbara Kee, PhD
Andrew Koh, PhD
Anthony Kossiakoff, PhD
Stephen Kron, MD, PhD
Ernst Lengyel, MD, PhD
Mark Lingen, DDS, PhD
Kay Macleod, PhD
Megan McNerney, MD, PhD
Raymond Moellering, PhD
Alex Muir, PhD
Scott Oakes, MD
Tao Pan, PhD
Sean Pitroda, MD
Andrea Piunti, PhD
Glenn Randall, PhD
Ilaria Rebay, PhD
Marsha Rosner, PhD
Alex Ruthenburg, PhD
Michael Thirman, MD
Samuel Volchenboum, MD, PhD
Amittha Wickrema, PhD
Chung-I Wu, PhD
Xiaoyang Wu, PhD
Lixing Yang, PhD
Yingming Zhao, PhD
Anindita Basu, PhD
Jennifer Bennett, MD
Eric Beyer, MD, PhD
Mengjie Chen, PhD
Guangbin Dong, PhD
Michael Drazer, MD
Nickolai Dulin, PhD
Sandeep Gurbuxani, MD, PhD
Xin He, PhD
Akira Imamoto, PhD
Jessica Kandel, MD
Bruce Lahn, PhD
Hue Luu, MD
Gokhan Mutlu, MD
Marcelo Nobrega, MD, PhD
David Pincus, PhD
Samantha Riesenfeld, PhD
Carrie Rinker-Schaeffer, PhD
Benoit Roux, PhD
Wei-Jen Tang, PhD
Weixin Tang, PhD
Juan Jose Apiz Saab, BS
Damian Berardi, PhD
Mohansrinivas Chennakesavalu, BS
Michele Ciboddo, MD
Rosemary Huggins, BS
Matthew Jotte, BS
Raven Watson, BA
Emma Anne Wilkinson, BS
Dongbo Yang, BS, MS
Anqi Yu, BS