Immunology and Cancer

Leadership
Program Leaders: Thomas Gajewski, MD, PhD, and Justin Kline, MD
Assistant Program Leader: Yuxuan (Phoenix) Miao, PhD
Community Research Advisor: Ramona Burress
The overall goals of the Immunology and Cancer Program are to understand the interaction between the host immune system and malignant tumors, and to manipulate that interaction to promote immune-mediated tumor destruction in patients with cancer. In recent years, tumor immunotherapy has revolutionized the way we treat some kinds of cancer.
These therapies, however, are not effective for all tumor types or all patients. Advances in our understanding of the cellular mechanisms by which the immune system fails to spontaneously reject cancer from a more global perspective will allow for innovations in immune-based therapies as well as optimization of current strategies.
Key Research Themes
- Perform basic science investigations in immunology relevant to cancer (e.g., innate immunity, lymphocyte activation and peripheral inflammation/tolerance regulation)
- Generate and interrogate preclinical mouse models of anti-tumor immunity
- Design and conduct clinical studies of human anti-tumor immunity and novel immunotherapies
Erin Adams, PhD
Maria-Luisa Alegre, MD, PhD
Nicolas Chevrier, PhD
Thinle Chodon, MD, PhD
Anita Chong, PhD
Marcus Clark, MD
Axel Concepcion, PhD
Daria Esterhazy, PhD
Thomas Gajewski, MD, PhD
Tatyana Golovkina, PhD
Jun Huang, PhD
Justin Kline, MD
Richard Koya, MD, PhD
James LaBelle, MD, PhD
Junko Matsuzaki, PhD
Yuxuan (Phoenix) Miao, PhD
Adekunle Odunsi, MD, PhD
Eric Pamer, MD
Joon Seok Park, MD, PhD
Pankti Reid, MD, MPH
Peter Savage, PhD
Hans Schreiber, MD, PhD
Lin Shen, MD, PhD
Melody A. Swartz, PhD
Randy F. Sweis, MD
Jonathan Trujillo, MD
Takemasa Tsuji, PhD
Santiago Acero Bedoya
Hajime Asada
Nicholas W. Asby
Stephen Barrett
Vivek Behera
Chufan Cai
Robert Bruce Cameron
Alexandra Cassano
Kevin Chang
Joanna Chorazeczewski
Maia Clare
Madeleine S. Durkee
Hao Fan
Colleen R. Foley
Camryn Garza
Olivia Hansen
Emily Higgs
Jacobi B. Hines
Jocelyn Hsu
Yifei Hu
Ina Jani
Xiaomin Jiang
Tyler Jones
Hannah Knight
Montserrat Kwan
Yaopeng Li
Taokun Luo
Margo E. MacDonald
Ricardo A. Mora
Rosemary E. Morman
Long Chi Nguyen
Benjamin Nicholson
Geoffrey R. Parriott
Eric Perkey
Alexandra Rojek
Martin N. Sepulveda
Kristen Shema
Lauren Y. Sheu
Shrey Sindhwani
Ruxandra Tonea
Jiayi Tu
Liangliang Wang
Sidney Wang
Thomas Wang
Adam M. Weiss
Sara Woessner
Senlin Xu
Allen C. Zhu
Nicholas Zolnerowich