Cancer cells cooperate to fight off the immune system and overcome therapy

New research from the lab of Thomas Gajewski, MD, PhD, showed that tumor cells can escape T cell killing during immunotherapy by using “clonal cooperation.” This work suggests that early treatment with immunotherapies may be more effective, before tumor cell heterogeneity emerges.

Six years after CAR T-cell therapy for lymphoma, patient still cancer-free
Sonali Smith, MD: Undaunted by the challenges of lymphoma