Gender
All
Age Group
40 Years and up
Accepting Healthy Volunteers
No
Inclusion Criteria
- Subjects with IPF aged ≥ 40 years at the time of signing the informed consent.
- Diagnosis of IPF within 7 years prior to screening that is supported by centrally
read chest high-resolution computed tomography (HRCT) obtained at screening and
verification of usual interstitial pneumonia.
- If on pirfenidone or nintedanib, participants must have been on a stable dose for at
least 90 days prior to screening.
- If not currently on pirfenidone or nintedanib, participants must not have received
either of these medications within 28 days prior to screening.
- Women who are of childbearing potential must have a highly effective form of
contraception and must provide a negative urine/serum pregnancy test.
- Men who are sexually active with women of childbearing potential agree to use male
barrier contraception.
Exclusion Criteria
- History of stroke or transient ischemic attack within 3 months prior to screening.
- Participants who exhibit symptoms of heart failure at rest.
- Participants who have a current malignancy or a previous malignancy with less than 2
years free of recurrence or a biopsy that is suspicious for malignancy and the
possibility of malignancy cannot be reasonably excluded following additional
clinical, laboratory, or other diagnostic evaluations.
- Other protocol-defined Inclusion/Exclusion criteria apply.